Peyronie’s disease is traditionally thought to be a localized contracture of the tunica albuginea of the penis that can result in plaque formation, leading to penile curvature, shortening, deformity, difficulty achieving erection and generalized erectile dysfunction. Since the medical community is unsure about what causes Peyronie’s Disease, it is thought that a possible cause could be autoimmune, genetic or micro trauma related. The Priapus Shot (P-Shot), performed by Dr. Seiler, can greatly reduce the symptoms of Peyronie’s disease and even be near curative.